Azathioprine belongs to a group of drugs known as immune suppressants. It is used to prevent organ rejection in people who have had a kidney transplant. Azathioprine is usually taken with other medicines so that the new kidney can function normally. Azathioprine is also used to treat rheumatoid arthritis. In this condition, the body’s immune system (immune system) attacks healthy joints.
Azathioprine is used in kidney transplantation and the treatment of rheumatoid arthritis or atherosclerosis.
What is the dosage of azathioprine?
Take azathioprine as directed by your doctor and usually once or twice a day orally.
Take azathioprine with food to reduce stomach upset.
Dosage is based on medical condition, weight, and response to treatment.
Do not increase your dose or use this medicine more or more than the prescribed time.
It may take 2 months for osteoarthritis to improve your symptoms.
If your condition does not improve after 3 months of treatment, tell your doctor.
The dosage required for kidney transplantation:
The amount needed to prevent transplant rejection and minimize toxicity will vary from patient to patient.
The initial dose is usually 3 to 5 mg/kg per day, starting at the time of transplantation.
In kidney transplantation, it is usually given as a single daily dose daily and in minor cases 1 to 3 days before transplantation.
Dose reduction to a maintenance rate of 1 to 3 mg/kg/day is usually possible.
The required dose of rheumatoid arthritis:
Azathioprine is usually given daily.
The initial dose should be one dose or twice a day.
If there is no serious toxicity and the initial response is unfavorable, the dose may be increased.
It starts from six to 8 weeks and then starts systematically at 4-week intervals.
Therapeutic response usually occurs after 6 to 8 weeks of treatment.
Patients who do not recover after 12 weeks may be resistant to treatment.
It may persist for a long time in patients who have a clinical response, but patients must be carefully monitored.
To reduce the risk of poisoning, a gradual dose reduction should be sought.
Note: What you are reading is only an awareness-raising aspect and is in no way a substitute for your doctor’s advice. Be sure to see a specialist to take medication, be aware of side effects, drug interactions, and other related issues.