What is azathioprine and what is its use? (part2)


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What is azathioprine and what is its use? (part2)

What is azathioprine

What are the side effects of azathioprine?

Azathioprine oral tablets do not cause drowsiness but can cause other side effects.

Common side effects:

The most common side effects that occur withAzathioprine are:

  • Low white blood cell count
  • Infections
  • Stomach problems
  • Nausea, diarrhea, and vomiting

Serious side effects:

  • nausea and vomiting
  • Diarrhea
  • Skin rash
  • Fever
  • Body aches or bruises
  • Increased liver enzyme levels
  • Liver damage
  • Vertigo
  • low blood pressure

These problems usually occur in the first few weeks of taking the medicine.

Symptoms of pancreatitis may include:

  • Severe abdominal pain
  • Fatty stools
  • Severe fatigue
  • Excess weight loss

Allergic side effects:

A severe allergic reaction whose symptoms may include the following:

  • Chest tightness
  • Itching
  • Swelling of the face, lips, tongue, or throat.

What are the precautions and warnings for taking azathioprine?

Tell your doctor or pharmacist before takingAzathioprine if you are allergic to it or mercaptopurine.

Azathioprine may increase the risk of skin cancer. Limit your time in the sun. Avoid tanning booths and sunlights. Use sunscreen outdoors and wear protective clothing.

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Your doctor may advise you to avoid phototherapy while using this product.

Azathioprine can put you at risk for infection or make your current infections worse. Consult your doctor if you are prone to infection or further details.

Before surgery, tell your doctor or dentist about all the products you use (including prescription, over-the-counter, and herbal products).

Azathioprine can put you at risk for infection or make your current infections worse.

Medical record:

Before using azathioprine, tell your doctor or pharmacist about your medical history, for example:

  • kidney disease
  • Liver disease
  • Cancer
  • Some enzymatic disorders (TPMT deficiency, NUDT15 deficiency)


Do not get vaccinated without your doctor’s consent.

Avoid contact with people who have recently received a live vaccine (such as the nasal flu vaccine).

Azathioprine and pregnancy:

Because azathioprine is absorbed through the skin and lungs and may harm the newborn.

Women who are or may become pregnant should not take this medicine or inhale pill dust.

What drugs interact with azathioprine?

Drug interactions may change the way your medications work or increase your risk of serious side effects.

Important Note: Azathioprine is very similar to mercaptopurine. Do not use mercaptopurine-containing medicines while using azathioprine.

Some products that may interact withAzathioprine include:


Previous or current use of certain cancer drugs (such as cyclophosphamide, melphalan)

Other drugs that weaken the immune system or increase the risk of infection (such as rituximab, tofacitinib)

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